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021-54845833/15800441009
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Background: |
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CNOT7 |
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Immunogen: |
Fusion protein of human CNOT7 |
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Full name: |
CCR4-NOT transcription complex subunit 7 |
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Synonyms: |
CAF1; CAF-1; Caf1a; hCAF-1 |
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SwissProt: |
Q9UIV1 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
50-100 |
