购物车
帮助
021-54845833/15800441009
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Background: |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
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Applications: |
WB |
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Name of antibody: |
TNNI3(Phospho-Thr142) |
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Immunogen: |
Peptide sequence around phosphorylation site of Threonine 142 (R-P-T(p)-L-R) derived from Human TNNI3. |
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Full name: |
troponin I type 3 (cardiac) |
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Synonyms： |
CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF |
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SwissProt: |
P19429 |
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WB Predicted band size: |
24 kDa |
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WB Positive control: |
Mouse heart tissue lysates |
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WB Recommended dilution: |
500-1000 |
