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ÖÐÎÄÃû³Æ£º Íÿ¹IL6ST¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-IL6ST rabbit polyclonal antibody

±ð    Ãû£º CD130; GP130; CDW130; IL-6RB

Ïà¹ØÀà±ð£º Ò»¿¹

´¢    ´æ£º Àä¶³£¨-20¡æ£©

¿¹    Ô­£º IL6ST

ËÞ    Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º Unconjugate

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Background:

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

Applications:

ELISA, IHC

Name of antibody:

IL6ST

Immunogen:

Fusion protein of human IL6ST

Full name:

interleukin 6 signal transducer

Synonyms£º

CD130; GP130; CDW130; IL-6RB

SwissProt:

P40189

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

30-150





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