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    µ±Ç°Î»ÖÃ: Ê×Ò³ > ¿ÆÑвúÆ· > ¿ÆÑп¹Ìå > Ò»¿¹ > Íÿ¹NTRK1(Phospho-Tyr757)¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹NTRK1(Phospho-Tyr757) ¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-NTRK1(Phospho-Tyr757) rabbit polyclonal antibody


    ±ð       Ãû£º MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA


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    ´¢        ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â


    ËÞ       Ö÷£º Rabbit


    ¿¹       Ô­£º NTRK1(Phospho-Tyr757)


    ·´Ó¦ÖÖÊô£º Human Mouse


    ±ê  ¼Ç  Î Unconjugate


    ¿Ë¡ÀàÐÍ£º Unconjugate


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    Background:

    This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

    Applications:

    IHC

    Name of antibody:

    NTRK1(Phospho-Tyr757)

    Immunogen:

    Peptide sequence around phosphorylation site of tyrosine 757 (E-V-Y(p)-A-I) derived from Human Trk A.

    Full name:

    neurotrophic tyrosine kinase, receptor, type 1

    Synonyms£º

    MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA

    SwissProt:

    P04629

    IHC positive control:

    Human brain tissue

    IHC Recommend dilution:

    50-100




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