ÖÐÎÄÃû³Æ£º Íÿ¹NTRK1(Phospho-Tyr757) ¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-NTRK1(Phospho-Tyr757) rabbit polyclonal antibody
±ð Ãû£º MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º NTRK1(Phospho-Tyr757)
·´Ó¦ÖÖÊô£º Human Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º Unconjugate
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Background: |
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
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Applications: |
IHC |
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Name of antibody: |
NTRK1(Phospho-Tyr757) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 757 (E-V-Y(p)-A-I) derived from Human Trk A. |
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Full name: |
neurotrophic tyrosine kinase, receptor, type 1 |
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Synonyms£º |
MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA |
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SwissProt: |
P04629 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |

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021-54845833/15800441009
