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Ó¢ÎÄÃû³Æ£º Anti-BRAF(Ab-446) rabbit polyclonal antibody
±ð Ãû£º NS7; BRAF1; RAFB1; B-RAF1
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¿¹ Ô£º BRAF(Ab-446)
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. |
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Applications: |
WB, IHC |
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Name of antibody: |
BRAF(Ab-446) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human B-RAF around the phosphorylation site of serine 446 (R-D-S(p)-S-D). |
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Full name: |
B-Raf proto-oncogene, serine/threonine kinasep |
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Synonyms£º |
NS7; BRAF1; RAFB1; B-RAF1 |
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SwissProt: |
P15056 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
84 kDa |
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WB Positive control: |
293 cells treated with insulin (0.01U/ml, 15mins) lysate |
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WB Recommended dilution: |
500-3000 |


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021-54845833/15800441009
