购物车
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021-54845833/15800441009
中文名称：兔抗BCCIP多克隆抗体
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Background: |
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
BCCIP |
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Immunogen: |
Fusion protein of human BCCIP |
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Full name: |
BRCA2 and CDKN1A interacting protein |
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Synonyms: |
TOK1; TOK-1 |
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SwissProt: |
Q9P287 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
TM4 cell lysate |
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WB Recommended dilution: |
200-1000 |
