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021-54845833/15800441009
中文名称：兔抗COL9A1多克隆抗体
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Background: |
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
COL9A1 |
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Immunogen: |
Fusion protein of human COL9A1 |
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Full name: |
collagen type IX alpha 1 chain |
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Synonyms: |
MED; EDM6; STL4; DJ149L1.1.2 |
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SwissProt: |
P20849 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
