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Ó¢ÎÄÃû³Æ£º Anti-PAK2(Phospho-Ser141) polyclonal antibody
±ð Ãû£º p21 (RAC1) activated kinase 2; PAK65; PAKgamma
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¿¹ Ô£º PAK2(Phospho-Ser141)
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
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Applications: |
WB |
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Name of antibody: |
PAK2(Phospho-Ser141) |
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Immunogen: |
Synthetic peptide of human PAK2 |
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Full name: |
p21 (RAC1) activated kinase 2 |
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Synonyms: |
PAK65; PAKgamma |
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SwissProt: |
Q13177 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
HepG2 cells treated with Adriamycin (0.5uM, 24hours) and Jurkat cells treated with PMA (125ng/ml, 30mins) |
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WB Recommended dilution: |
500-1000 |

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