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  • Íÿ¹PAK2(Phospho-Ser197)¶à¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ£º Íÿ¹PAK2(Phospho-Ser197) ¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-PAK2(Phospho-Ser197) rabbit polyclonal antibody


±ð       Ãû£º PAK65; PAKgamma


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ËÞ      Ö÷£º Rabbit


¿¹      Ô­£º PAK2(Phospho-Ser197)


·´Ó¦ÖÖÊô£º Human


±ê ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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Background:

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Applications:

IHC

Name of antibody:

PAK2(Phospho-Ser197)

Immunogen:

Peptide sequence around phosphorylation site of Serine 197(T-R-S(p)-V-I) derived from Human PAK2.

Full name:

p21 protein (Cdc42/Rac)-activated kinase 2

Synonyms£º

PAK65; PAKgamma

SwissProt:

Q13177

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100






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