ÖÐÎÄÃû³Æ£ºÍÿ¹CAMK2A(Ab-286)¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-CAMK2A(Ab-286) rabbit polyclonal antibody
±ð Ãû£º CAMKIIN; CAM-KIIN
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º CAMK2A(Ab-286)
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. |
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Applications: |
WB, IF |
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Name of antibody: |
CAMK2A(Ab-286) |
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Immunogen: |
Synthetic peptide of human CAMK2A(Ab-286) |
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Full name: |
calcium/calmodulin dependent protein kinase II alpha |
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Synonyms: |
CAMKA |
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SwissProt: |
Q9UQM7 |
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WB Predicted band size: |
54 kDa |
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WB Positive control: |
Hela cells |
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WB Recommended dilution: |
500-1000 |
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IF positive control: |
Human hippocampal region tissue from the falling sickness disease |
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IF Recommend dilution: |
100-200 |

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