购物车
帮助
021-54845833/15800441009
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Background: |
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
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Applications: |
WB |
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Name of antibody: |
EIF2AK3(Phospho-Thr982) |
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Immunogen: |
Peptide sequence around phosphorylation site of threonine 982(A-R-H(p)-T-G) derived from Human PEK/PERK. |
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Full name: |
eukaryotic translation initiation factor 2 alpha kinase 3 |
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Synonyms: |
PEK; WRS; PERK |
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SwissProt: |
Q9NZJ5 |
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WB Predicted band size: |
130 kDa |
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WB Positive control: |
453 and AD293 cell lysates |
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WB Recommended dilution: |
500-1000 |
