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021-54845833/15800441009
中文名称：小鼠抗EIF2S1单克隆抗体
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Background: |
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]). |
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Applications: |
WB, IF, IP |
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Name of antibody: |
EIF2S1 |
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Immunogen: |
Fusion protein of human EIF2S1 |
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Full name: |
eukaryotic translation initiation factor 2 subunit alpha |
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Synonyms: |
EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha |
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SwissProt: |
P05198 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
K562, COS7, 3T3, C2C12, MCF-7, C6 and Hela cell lysates |
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WB Recommended dilution: |
1000-5000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
100-200 |
