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  • Íÿ¹CCDC88A¶à¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ£ºÍÿ¹CCDC88A¶à¿Ë¡¿¹Ìå 

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Anti-CCDC88A rabbit polyclonal antibody

±ð      Ãû£º APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212

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¿¹      Ô­£º CCDC88A

ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse

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Unconjugate

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rabbit polyclonal

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Background:

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, IHC

Name of antibody:

CCDC88A

Immunogen:

Synthetic peptide of human CCDC88A

Full name:

coiled-coil domain containing 88A

Synonyms£º

APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212

SwissProt:

Q3V6T2

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human cervical cancer and Human colon cancer

IHC Recommend dilution:

50-200




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