ÖÐÎÄÃû³Æ£ºÍÿ¹CCDC88A¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-CCDC88A rabbit polyclonal antibody
±ð Ãû£º APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
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¿¹ Ô£º CCDC88A
ËÞ Ö÷£º Rabbit
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CCDC88A |
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Immunogen: |
Synthetic peptide of human CCDC88A |
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Full name: |
coiled-coil domain containing 88A |
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Synonyms£º |
APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212 |
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SwissProt: |
Q3V6T2 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human cervical cancer and Human colon cancer |
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IHC Recommend dilution: |
50-200 |

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021-54845833/15800441009
