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Background: |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. |
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Applications: |
WB |
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Name of antibody: |
TOP2A(Ab-1343) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human TOP2A around the phosphorylation site of threonine 1343 (E-K-T(p)-D-D). |
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Full name: |
topoisomerase (DNA) II alpha 170kDa |
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Synonyms： |
TOP2; TP2A |
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SwissProt: |
P11388 |
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WB Predicted band size: |
174 kDa |
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WB Positive control: |
HepG2 cells lysate |
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WB Recommended dilution: |
500-3000 |
