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Background: |
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EPCAM |
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Immunogen: |
Fusion protein of human EPCAM |
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Full name: |
epithelial cell adhesion molecule |
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Synonyms: |
ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1 |
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SwissProt: |
P16422 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and Human prostate cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
35 kDa |
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WB Positive control: |
HT-29 cell lysate |
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WB Recommended dilution: |
1000-5000 |
