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中文名称：ASGR1抗原（重组蛋白）
英文名称： ASGR1 Antigen (Recombinant Protein)
别 名： HL-1; ASGPR; ASGPR1; CLEC4H1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 62-291 amino acids of human ASGR1 |
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Full name: |
asialoglycoprotein receptor 1 |
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Synonyms: |
HL-1; ASGPR; ASGPR1; CLEC4H1 |
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Swissprot: |
P07306 |
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Gene Accession: |
BC032130 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
