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Ó¢ÎÄÃû³Æ£º WDR45 Antigen (Recombinant Protein)

±ð      Ãû£º WD repeat domain 45; JM5; NBIA4; NBIA5; WDRX1; WIPI4; WIPI-4

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Fusion protein corresponding to C terminal 200 amino acids of human WDR45

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Full name:

WD repeat domain 45

Synonyms:

JM5; NBIA4; NBIA5; WDRX1; WIPI4; WIPI-4

Swissprot:

Q9Y484

Gene Accession:

BC000464

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.


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