购物车
帮助
021-54845833/15800441009
中文名称：ASCC1抗原（重组蛋白）
英文名称： ASCC1 Antigen (Recombinant Protein)
别 名： p50; CGI-18; ASC1p50
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human ASCC1 |
|
Full name: |
activating signal cointegrator 1 complex subunit 1 |
|
Synonyms: |
p50; CGI-18; ASC1p50 |
|
Swissprot: |
Q8N9N2 |
|
Gene Accession: |
BC012291 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. |
