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中文名称：ALDH8A1 抗原（重组蛋白）
英文名称： ALDH8A1 Antigen (Recombinant Protein)
别 名： aldehyde dehydrogenase 8 family, member A1; ALDH12; DJ352A20.2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 148-337 amino acids of human ALDH8A1 |
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Full name: |
aldehyde dehydrogenase 8 family, member A1 |
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Synonyms: |
ALDH12; DJ352A20.2 |
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Swissprot: |
Q9H2A2 |
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Gene Accession: |
BC113862 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. |
