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Ó¢ÎÄÃû³Æ£º BIRC2 Antigen (Recombinant Protein)

±ð       Ãû£º API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1

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Fusion protein corresponding to C terminal 250 amino acids of human BIRC2

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Full name:

Baculoviral IAP repeat containing 2

Synonyms:

API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1

Swissprot:

Q13490

Gene Accession:

BC016174

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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