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ÖÐÎÄÃû³Æ£º CHST11 ¿¹Ô­£¨ÖØ×éµ°°×£©

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CHST11 Antigen (Recombinant Protein)

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carbohydrate sulfotransferase 11; C4ST; C4ST1; C4ST-1; HSA269537

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Fusion protein corresponding to a region derived from 153-352 amino acids of human CHST11

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Full name:

carbohydrate sulfotransferase 11

Synonyms:

C4ST; C4ST1; C4ST-1; HSA269537

Swissprot:

Q9NPF2

Gene Accession:

BC013315

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.



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