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中文名称：CFHR1抗原（重组蛋白）
英文名称：CFHR1 Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
Fusion protein corresponding to a region derived from 22-330 amino acids of human CFHR1
概述
技术规格
Full name:
complement factor H-related 1
Synonyms:
CFHL, FHR1, HFL1, HFL2, CFHL1, H36-1, H36-2, CFHL1P, CFHR1P
Swissprot:
Q03591
Gene Accession:
BC016755
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
