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中文名称：TRAF4 抗原（重组蛋白）
英文名称： TRAF4 Antigen (Recombinant Protein)
别 名： TNF receptor associated factor 4; CART1; MLN62; RNF83
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 307-462 amino acids of human TRAF4 |
|
Full name: |
TNF receptor associated factor 4 |
|
Synonyms: |
CART1; MLN62; RNF83 |
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Swissprot: |
Q9BUZ4 |
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Gene Accession: |
BC001769 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. |
