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中文名称： EIF3H抗原（重组蛋白）
英文名称： EIF3H Antigen (Recombinant Protein)
别 名： EIF3S3; eIF3-p40; eIF3-gamma
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 300 amino acids of human EIF3H |
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Full name: |
eukaryotic translation initiation factor 3, subunit H |
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Synonyms: |
EIF3S3; eIF3-p40; eIF3-gamma |
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Swissprot: |
O15372 |
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Gene Accession: |
BC000386 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
