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Ó¢ÎÄÃû³Æ£º ASH2L Antigen (Recombinant Protein)

±ð      Ãû£º ASH2; Bre2; ASH2L1; ASH2L2

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Fusion protein corresponding to a region derived from 360-583 amino acids of human ASH2L


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Full name:

ASH2 like, histone lysine methyltransferase complex subunit

Synonyms:

ASH2; Bre2; ASH2L1; ASH2L2

Swissprot:

Q9UBL3

Gene Accession:

BC015936

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.


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