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中文名称：BCAT1抗原（重组蛋白）
英文名称： BCAT1 Antigen (Recombinant Protein)
别 名： BCT1; PP18; BCATC; ECA39; MECA39; PNAS121
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 3-301 amino acids of human BCAT1 |
|
Full name: |
branched chain amino acid transaminase 1 |
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Synonyms: |
BCT1; PP18; BCATC; ECA39; MECA39; PNAS121 |
|
Swissprot: |
P54687 |
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Gene Accession: |
BC033864 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. |
