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中文名称：PDIA5 抗原（重组蛋白）
英文名称： PDIA5 Antigen (Recombinant Protein)
别 名： protein disulfide isomerase family A member 5; PDIR
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 22-262 amino acids of human PDIA5 |
|
Full name: |
protein disulfide isomerase family A member 5 |
|
Synonyms: |
PDIR |
|
Swissprot: |
Q14554 |
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Gene Accession: |
BC001625 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants. |
