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中文名称：CALCOCO1 抗原（重组蛋白）
英文名称： CALCOCO1 Antigen (Recombinant Protein)
别 名： calcium binding and coiled-coil domain 1; Cocoa; PP13275; calphoglin
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 492-691 amino acids of human CALCOCO1 |
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Full name: |
calcium binding and coiled-coil domain 1 |
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Synonyms: |
Cocoa; PP13275; calphoglin |
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Swissprot: |
Q9P1Z2 |
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Gene Accession: |
BC003177 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3. |
