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中文名称：ECH1抗原（重组蛋白）
英文名称： ECH1 Antigen (Recombinant Protein)
别 名： HPXEL
储 存： 冷冻（-20℃）
概 述：
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Fusion protein corresponding to a region derived from 34-328 amino acids of human ECH1 |
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Full name: |
enoyl-CoA hydratase 1 |
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Synonyms: |
HPXEL |
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Swissprot: |
Q13011 |
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Gene Accession: |
BC011792 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |
