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中文名称： CHRNA4抗原（重组蛋白）
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Full name: |
cholinergic receptor, nicotinic, alpha 4 (neuronal) |
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Synonyms: |
EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4 |
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Swissprot: |
P43681 |
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Gene Accession: |
BC096290 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. |
