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    ÖÐÎÄÃû³Æ£º RNF40 ¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º RNF40 Antigen (Recombinant Protein)

    ±ð     Ãû£º ring finger protein 40, E3 ubiquitin protein ligase; BRE1B; RBP95; STARING

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    Fusion protein corresponding to C terminal 250 amino acids of human RNF40

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    Full name:

    ring finger protein 40, E3 ubiquitin protein ligase

    Synonyms:

    BRE1B; RBP95; STARING

    Swissprot:

    O75150

    Gene Accession:

    BC006133

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.


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