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中文名称：IRAK3抗原（重组蛋白）
英文名称： IRAK3 Antigen (Recombinant Protein)
别 名： ASRT5; IRAKM
概述
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Fusion protein corresponding to a region derived from 165-452 amino acids of human IRAK3 |
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Full name: |
interleukin-1 receptor-associated kinase 3 |
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Synonyms: |
ASRT5; IRAKM |
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Swissprot: |
Q9Y616 |
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Gene Accession: |
BC057800 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. |
