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中文名称： RBBP8抗原（重组蛋白）
英文名称： RBBP8 Antigen (Recombinant Protein)
别 名： RIM; COM1; CTIP; JWDS; SAE2; SCKL2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 603-902 amino acids of human RBBP8 |
|
Full name: |
retinoblastoma binding protein 8 |
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Synonyms: |
RIM; COM1; CTIP; JWDS; SAE2; SCKL2 |
|
Swissprot: |
Q99708 |
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Gene Accession: |
BC030590 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. |
