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中文名称：CASP2抗原（重组蛋白）
英文名称：CASP2 Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
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Fusion protein corresponding to N terminal 201 amino acids of human CASP2 |
技术规格
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Full name: |
Caspase-2 |
|
Synonyms: |
ICH1, NEDD2, CASP-2, NEDD-2 |
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Swissprot: |
P42575 |
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Gene Accession: |
BC002427 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
