购物车
帮助
021-54845833/15800441009
|
Fusion protein corresponding to N terminal 181 amino acids of human RASSF8 |
Full name:
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Synonyms:
HOJ1; C12orf2
Swissprot:
Q8NHQ8
Gene Accession:
BC030021
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
