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ÖÐÎÄÃû³Æ£ºÍÿ¹ATN1¶à¿Ë¡¿¹Ìå  

Ó¢ÎÄÃû³Æ£º Anti-ATN1 rabbit polyclonal antibody

±ð      Ãû£º atrophin 1; B37; HRS; NOD; DRPLA; D12S755E

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ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º ATN1

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Applications:

ELISA, IHC

Name of antibody:

ATN1

Immunogen:

Synthetic peptide of human ATN1

Full name:

atrophin 1

Synonyms:

B37; HRS; NOD; DRPLA; D12S755E

SwissProt:

P54259

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human ovarian cancer

IHC Recommend dilution:

40-200





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