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中文名称： 兔抗MICA多克隆抗体
英文名称： Anti-MICA rabbit polyclonal antibody
别 名： MHC class I polypeptide-related sequence A; MIC-A; PERB11.1
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： MICA
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MICA |
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Immunogen: |
Fusion protein of human MICA |
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Full name: |
MHC class I polypeptide-related sequence A |
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Synonyms: |
MIC-A; PERB11.1 |
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SwissProt: |
Q29983 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
50-200 |
