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    ÖÐÎÄÃû³Æ£ºÐ¡Êó¿¹FSCN1µ¥¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-FSCN1 mouse monoclonal antibody

    ±ð       Ãû£º fascin actin-bundling protein 1; HSN; SNL; p55; FAN1

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    ËÞ       Ö÷£º Mouse

    ¿¹       Ô­£º FSCN1

    ·´Ó¦ÖÖÊô£º Human

    ±ê  ¼Ç  Î Unconjugate

    ¿Ë¡ÀàÐÍ£º mouse monoclonal



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    Background:

    This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

    Applications:

    ELISA, WB

    Name of antibody:

    FSCN1

    Immunogen:

    Fusion protein of human FSCN1

    Full name:

    fascin actin-bundling protein 1

    Synonyms:

    HSN; SNL; p55; FAN1

    SwissProt:

    Q16658

    WB Predicted band size:

    55 kDa

    WB Positive control:

    HEPG2 whole cell lysate

    WB Recommended dilution:

    500-2000




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