购物车
帮助
021-54845833/15800441009
中文名称：兔抗ACTN1/2/3/4多克隆抗体
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Background: |
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB |
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Name of antibody: |
ACTN1/2/3/4 |
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Immunogen: |
Synthesized peptide derived from internal of human ACTN4. |
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Full name: |
actinin, alpha 1/2/3/4 |
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Synonyms： |
BDPLT15/CMD1AA/FSGS; FSGS1; ACTININ-4 |
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SwissProt: |
P12814/P35609/Q08043/O43707 |
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WB Predicted band size: |
103/104/103/105 kDa |
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WB Positive control: |
293 cells, Hela cells and A549 cells lysates |
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WB Recommended dilution: |
500-3000 |
