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  • Íÿ¹PRKAR2B(Ab-113)¶à¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ£º   Íÿ¹PRKAR2B(Ab-113) ¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º   Anti-PRKAR2B(Ab-113) rabbit polyclonal antibody


±ð       Ãû£º   PRKAR2; RII-BETA


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´¢      ´æ£º   Àä¶³£¨-20¡æ£© ±Ü¹â


¿¹     Ô­£º   PRKAR2B(Ab-113)


ËÞ     Ö÷£º    Rabbit


·´Ó¦ÖÖÊô£º   Human Mouse Rat


±ê ¼Ç Î    Unconjugate


¿Ë¡ÀàÐÍ£º   rabbit polyclonal


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Background:

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.

Applications:

WB, IHC

Name of antibody:

PRKAR2B(Ab-113)

Immunogen:

Synthesized non-phosphopeptide derived from human PKA-R2¦Â around the phosphorylation site of serine 113 (R-A-S(p)-V-C).

Full name:

protein kinase, cAMP-dependent, regulatory, type II, beta

Synonyms£º

PRKAR2; RII-BETA

SwissProt:

P31323

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

46 kDa

WB Positive control:

HepG2 cells and K562 cells lysates

WB Recommended dilution:

500-3000






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