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中文名称 : 兔抗NGEF多克隆抗体
英文名称 : Anti-NGEF rabbit polyclonal antibody
别 名 : neuronal guanine nucleotide exchange factor; EPHEXIN; ARHGEF27
抗 原 : NGEF
储 存 : 冷冻（-20℃）
宿 主 : Rabbit
反应种属 : Human, Mouse, Rat
标 记 物 : Unconjugate
相关类别 : 一抗
克隆类型 : rabbit polyclonal
技术规格
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Background: |
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity). |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
NGEF |
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Immunogen: |
Fusion protein of human NGEF |
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Full name: |
neuronal guanine nucleotide exchange factor |
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Synonyms: |
EPHEXIN; ARHGEF27 |
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SwissProt: |
Q8N5V2 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human liver cancer |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
82 kDa |
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WB Positive control: |
Rat brain tissue and Mouse brain tissue lysates |
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WB Recommended dilution: |
500-2000 |
