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    ÖÐÎÄÃû³Æ£ºÐ¡Êó¿¹MSH2µ¥¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-MSH2 mouse monoclonal antibody

    ±ð       Ãû£º mutS homolog 2; FCC1; COCA1; HNPCC; LCFS2; HNPCC1

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    ´¢       ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ       Ö÷£º Mouse

    ¿¹       Ô­£º MSH2

    ·´Ó¦ÖÖÊô£º Human

    ±ê  ¼Ç  Î Unconjugate

    ¿Ë¡ÀàÐÍ£º Mouse Monoclonal

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    Background:

    This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

    Applications:

    WB

    Name of antibody:

    MSH2

    Immunogen:

    Fusion protein of human MSH2

    Full name:

    mutS homolog 2

    Synonyms:

    FCC1; COCA1; HNPCC; LCFS2; HNPCC1

    SwissProt:

    P43246

    WB Predicted band size:

    105 kDa

    WB Positive control:

    CEM, Jurkat, 293T, K562 and A431 cell lysates

    WB Recommended dilution:

    1000-5000



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