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021-54845833/15800441009
中文名称： 兔抗UBR7多克隆抗体
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Background: |
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr7 (ubiquitin protein ligase E3 component n-recognin 7), also known as C14orf130 or N-recognin-7, is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
UBR7 |
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Immunogen: |
Fusion protein of human UBR7 |
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Full name: |
ubiquitin protein ligase E3 component n-recognin 7 (putative) |
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Synonyms: |
C14orf130 |
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SwissProt: |
Q8N806 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer;Human liver cancer |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
48 kDa |
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WB Positive control: |
Hela cell lysate |
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WB Recommended dilution: |
200-1000 |
