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Ó¢ÎÄÃû³Æ£º Anti-PRKAA1 rabbit polyclonal antibody
±ð Ãû£º protein kinase AMP-activated catalytic subunit alpha 1; AMPK; AMPKa1
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PRKAA1
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PRKAA1 |
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Immunogen: |
Synthetic peptide of human PRKAA1 |
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Full name: |
protein kinase AMP-activated catalytic subunit alpha 1 |
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Synonyms: |
AMPK; AMPKa1 |
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SwissProt: |
Q13131 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human esophagus cancer |
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IHC Recommend dilution: |
30-150 |


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