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021-54845833/15800441009
中文名称：兔抗ARRB2多克隆抗体
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Background: |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ARRB2 |
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Immunogen: |
Synthetic peptide of human ARRB2 |
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Full name: |
arrestin beta 2 |
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Synonyms: |
ARB2; ARR2; BARR2 |
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SwissProt: |
P32121 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
40 kDa |
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WB Positive control: |
HEPG2 and Hela cell lysates |
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WB Recommended dilution: |
200-1000 |
