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021-54845833/15800441009
Background:
HtrA3, also known as PRSP (pregnancy-related serine protease), is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
Applications:
ELISA, IHC
Name of antibody:
HTRA3
Immunogen:
Synthetic peptide of human HTRA3
Full name:
HtrA serine peptidase 3
Synonyms：
Prsp; Tasp
SwissProt:
P83110
ELISA Recommended dilution:
1000-5000
IHC positive control:
Human liver cancer
IHC Recommend dilution:
50-200
技术规格
