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Ó¢ÎÄÃû³Æ£º Anti-MRPL48 rabbit polyclonal antibody
±ð Ãû£º mitochondrial ribosomal protein L48; L48MT; CGI-118; HSPC290; MRP-L48
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º MRPL48
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MRPL48 |
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Immunogen: |
Fusion protein of human MRPL48 |
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Full name: |
mitochondrial ribosomal protein L48 |
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Synonyms: |
L48MT; CGI-118; HSPC290; MRP-L48 |
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SwissProt: |
Q96GC5 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer and Human gastric cancer |
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IHC Recommend dilution: |
150-300 |


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