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021-54845833/15800441009
中文名称： 小鼠抗ACVRL1单克隆抗体
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Background: |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
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Applications: |
WB |
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Name of antibody: |
ACVRL1 |
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Immunogen: |
Fusion protein of human ACVRL1 |
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Full name: |
activin A receptor like type 1 |
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Synonyms: |
HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1 |
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SwissProt: |
P37023 |
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WB Predicted band size: |
56 KD |
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WB Positive control: |
Jurkat, MCF7, K562 and Hela cell lysates |
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WB Recommended dilution: |
500-2000 |
