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    ÖÐÎÄÃû³Æ£º   Íÿ¹MNDA¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º   Anti-MNDA rabbit polyclonal antibody

    ±ð      Ãû£º   PYHIN3


    ´¢      ´æ£º   Àä¶³£¨-20¡æ£© ±Ü¹â


    ¿¹     Ô­£º   MNDA


    ËÞ     Ö÷£º   Rabbit


    ·´Ó¦ÖÖÊô£º  Human


    Ïà¹ØÀà±ð£º  Ò»¿¹


    ±ê ¼Ç  Î  Unconjugate


    ¿Ë¡ÀàÐÍ£º  Unconjugate


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    Background:

    The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

    Applications:

    WB

    Name of antibody:

    MNDA

    Immunogen:

    Synthesized peptide derived from C-terminal of human MNDA.

    Full name:

    myeloid cell nuclear differentiation antigen

    Synonyms£º

    PYHIN3

    SwissProt:

    P41218

    WB Predicted band size:

    46 kDa

    WB Positive control:

    LOVO cells lysate

    WB Recommended dilution:

    500-3000




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