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中文名称： 兔抗SCN11A多克隆抗体
英文名称： Anti-SCN11A rabbit polyclonal antibody
别 名： NaN; SNS-2; NAV1.9; SCN12A
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： SCN11A
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate 、
克隆类型： rabbit polyclonal
技术规格
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Background: |
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SCN11A |
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Immunogen: |
Synthetic peptide of human SCN11A |
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Full name: |
sodium channel, voltage-gated, type XI, alpha subunit |
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Synonyms： |
NaN; SNS-2; NAV1.9; SCN12A |
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SwissProt: |
Q9UI33 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human breast cancer and Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |
